Histamine N-methyltransferase in NS-ARID In Heidari et al, [epub ahead of print] PMID: 26206890, we report the association of homozygous missense mutations with non-syndromic autosomal recessive ID in two consanguineous families, one of Kurdish origin, the other of Turkish origin. We also speculate whether heterozygous truncating mutations of CNVs disrupting HNMT may be a risk factor in ASD, ID, schizophrenia and bipolar disorder